Amphotericin B is a medication used to treat potentially life-threatening fungal infections. Like all medications, it can cause side effects. Here are some of the positive and negative aspects of Amphotericin B:

Positive:

• Can treat serious fungal infections
• Can be used in pediatric and elderly patients
• Has a lower incidence of infusion-related, cardiovascular, and renal adverse events compared to amphotericin B deoxycholate

Negative:

• Can cause serious side effects
• Common adverse events include chills, fever, nausea, vomiting, and respiratory adverse events
• Can cause nephrotoxicity (kidney damage)
• Can cause hypokalemia (low potassium levels) and hypomagnesemia (low magnesium levels)
• Can cause allergic reactions
• Can interact with other medications, such as lomustine and magnesium chloride

The ingredients of Amphotericin B include amphotericin B itself, as well as other components in the formulation.