The statement that the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS 2) supersedes provincial and territorial legislation in Canada is false. TCPS 2 serves as the main ethical guideline for research involving humans in Canada, developed by Canada's three federal research agencies. However, it does not override or supersede provincial and territorial laws. Instead, TCPS 2 is designed to be consistent with Canadian laws and regulations, and researchers must comply with both TCPS 2 standards and relevant provincial or territorial legislation. Generally, if there is a conflict, the stricter standard applies. Thus, TCPS 2 provides ethical guidance but does not have legal authority over provincial or territorial legislation.