The song "Bed Chem" by Sabrina Carpenter explores the theme of sexual chemistry and attraction between two people. The lyrics describe a strong physical and emotional connection that the singer imagines having with a new crush. Sabrina details moments of meeting, mutual attraction, and fantasies about the chemistry they would share in an intimate setting. The song contains suggestive lyrics about the intense connection and playful, sweet talk during their interactions. Key lyrics from the chorus include:

• "But I bet we'd have really good bed chem / How you pick me up, pull ’em down, turn me ’round / Oh, it just makes sense / How you talk so sweet when you’re doin’ bad things."
• "How you're lookin’ at me, yeah, I know what that means / And I’m obsessed / Are you free next week? / I bet we'd have really good bed chem."
• "And I bet the thermostat's set at six-nine, and I bet it's even better than in my head."

The song hints at a romantic interest likely inspired by a real person, with references to a "cute guy with the wide, blue eyes" and distance across time zones, adding a personal and teasing dimension to the lyrics.