It is generally safe to drink alcohol in moderation while taking amoxicillin, as there is no direct harmful interaction between the two. However, drinking alcohol may worsen common side effects of amoxicillin such as nausea, dizziness, stomach upset, and gastrointestinal issues. Alcohol can also weaken the immune system, cause dehydration, and potentially slow down the healing process from the infection you are being treated for. Therefore, it is advisable to avoid or limit alcohol consumption during your course of amoxicillin to help your body recover effectively and minimize side effects. After finishing the antibiotic, waiting at least 48 hours before drinking alcohol is recommended to allow the medication to fully clear from your system. For individual advice, consult your healthcare provider, especially if you have other medical conditions or take multiple medications.