It is generally safe to drink alcohol while taking flucloxacillin. There are no major harmful interactions between flucloxacillin and alcohol. However, flucloxacillin can sometimes cause side effects like nausea and diarrhea, and alcohol might worsen these symptoms. Additionally, drinking alcohol can slow down recovery from infection and may make symptoms like dehydration and impaired immune response worse. It is best to drink alcohol in moderation or avoid it to support faster recovery, and to avoid alcohol for a few days after finishing the antibiotic course to be safe. Summary:

• Drinking alcohol while on flucloxacillin is not strictly contraindicated.
• Alcohol may worsen side effects such as nausea and diarrhea.
• Alcohol can impair immune recovery and hydration status.
• Moderation or avoidance of alcohol is recommended for better recovery.
• Avoid alcohol for 2-3 days after completing flucloxacillin treatment.

This aligns with the advice from NHS and other medical sources.