Neosporin is generally not recommended for use on cats. While it contains useful antibiotics, it can cause itchy skin or allergic reactions in cats. More seriously, if cats lick the ointment and ingest it, they may experience side effects such as vomiting, diarrhea, anaphylactic shock, and other allergic symptoms. Because cats tend to groom themselves extensively, there is a high risk they will ingest Neosporin, potentially leading to life- threatening allergic reactions. Veterinarians often advise using safer alternative medications for cat wounds and strictly recommend using Neosporin only under veterinary guidance, often with precautions like an e-collar to prevent licking. Specifically, Neosporin contains bacitracin, neomycin, and polymyxin B, and polymyxin B has been linked to severe allergic reactions in cats. If a cat shows any signs of allergic reaction or distress after Neosporin use, a vet should be consulted immediately. In summary, Neosporin is not safe for routine use on cats and should only be used if a veterinarian explicitly recommends it and monitors for side effects.