Mushrooms containing psilocybin (commonly called "shrooms" or magic mushrooms) generally do not show up on standard drug tests such as the common 5-panel, 8-panel, 10-panel, or 12-panel urine tests used by most employers or routine screenings. These standard tests typically screen for substances like THC, cocaine, amphetamines, opioids, and PCP, but they do not include psilocybin or its metabolite psilocin

. However, specialized drug tests designed specifically to detect hallucinogens can identify psilocybin or psilocin in urine, blood, saliva, hair, or fingernail samples. These specialized tests are less common, more expensive, and usually only used when there is a strong suspicion of psilocybin use. For example:

• Urine tests can detect psilocybin for up to about 24 hours after ingestion.
• Blood tests have a shorter detection window, often only a few hours post-use.
• Hair and fingernail tests can detect psilocybin use for up to 3 months or even 6 months, respectively

Psilocybin is rapidly metabolized into psilocin and cleared from the body relatively quickly, which limits the detection window in most biological samples

. In summary:

• Standard drug tests do not detect psilocybin mushrooms.
• Specialized tests can detect psilocybin but are rarely used in routine screening.
• Detection windows are short for urine and blood tests but longer for hair and nail tests.

Thus, unless a specialized test is specifically ordered, psilocybin mushrooms will not show up on typical drug tests