The main cast of Fantastic Beasts and Where to Find Them (2016) includes:

• Eddie Redmayne as Newt Scamander, a British magizoologist and the protagonist of the film.
• Katherine Waterston as Tina Goldstein, a former Auror working for MACUSA.
• Dan Fogler as Jacob Kowalski, a No-Maj (Muggle) aspiring baker who becomes involved with the magical world.
• Alison Sudol as Queenie Goldstein, Tina's free-spirited sister with Legilimency abilities.
• Ezra Miller as Credence Barebone, a secret Obscurial wizard.
• Samantha Morton as Mary Lou Barebone, leader of an anti-wizard group.
• Jon Voight as Henry Shaw Sr., a newspaper owner.
• Carmen Ejogo as Seraphina Picquery, President of MACUSA.
• Colin Farrell as Percival Graves, a high-ranking Auror who is later revealed to be Gellert Grindelwald in disguise.
• Ron Perlman as the voice of Gnarlak, a goblin gangster.
• Faith Wood-Blagrove as Modesty Barebone, one of Mary Lou's adopted children.

Additional cast members include Jenn Murray, Gemma Chan, Ronan Raftery, Josh Cowdery, Kevin Guthrie, and Johnny Depp as Gellert Grindelwald in later scenes

. Eddie Redmayne's portrayal of Newt Scamander was especially noted for its subtlety and British understated heroism, with J.K. Rowling personally involved in the casting process