Drunk Elephant is a skincare brand that is committed to using only ingredients that either directly benefit the health of the skin or support the integrity of their formulations. They never take into account whether something is synthetic or natural, instead choosing ingredients based on biocompatibility. The brand avoids using the "Suspicious 6" ingredients that they believe are at the root of almost every skin issue, including essential oils, drying alcohols, silicones, chemical sunscreens, fragrances/dyes, and SLS.

Drunk Elephant products are free of essential oils, silicones, and fragrance. They are formulated with healthy pH levels, small molecular structure that’s easily absorbed, and effective active ingredients that also support and maintain the skin’s acid mantle.

The Drunk Elephant Protini Polypeptide Firming Refillable Moisturizer is a cream with some proteins and is created "with crazy levels of amino acids, signal peptides and safe, synthetic" ingredients. The cream has a pH of 4.0 and is free of essential oils, silicones, and fragrance.

The Drunk Elephant B-Hydra Intensive Hydration Serum with Hyaluronic Acid is a serum that is free of essential oils, silicones, and fragrance.

Overall, Drunk Elephant products are formulated with biocompatible ingredients that are free of the "Suspicious 6" ingredients. They are designed to support and maintain the skins acid mantle and are free of essential oils, silicones, and fragrance.