Addictive disorders and substance use disorders are similar in several ways but also differ in key aspects. Similarities:

• Both involve compulsive engagement in rewarding behaviors or substances despite negative consequences.
• They share a neurobiological basis involving brain chemistry and the reward system, leading to dependency and cravings.
• Both disorders lead to psychological effects such as lying, stealing, cheating, anger, depression, frustration, and anxiety.
• Treatment approaches such as detoxification, behavioral therapy, and support groups can be effective for both.
• Both are chronic brain disorders characterized by compulsive behavior and potential relapse.
• They share comorbidities with mental illnesses and may co-occur.
• Both result in impairment in social, occupational, and other major life areas.

Differences:

• Substance use disorders involve the misuse of substances like alcohol, opioids, or stimulants, causing physical dependency with tolerance and withdrawal symptoms.
• Addictive disorders (behavioral addictions) involve compulsive behaviors without substance ingestion, such as gambling or shopping.
• Withdrawal symptoms are substance-specific and physiological in substance use disorders, while behavioral addictions may involve psychological withdrawal.
• Substance use disorders often require managing physical detoxification, which is not present in behavioral addictions.
• Diagnostic criteria for substance use disorders are well-established (e.g., DSM-5) with a focus on use quantity, tolerance, and withdrawal; behavioral addictions rely more on behavioral patterns and psychological criteria.

In summary, addictive disorders and substance use disorders are closely related in their brain and behavioral mechanisms and often overlap, but they differ mainly in the presence of a substance and the physical aspects of dependency in substance use disorders.