Levofloxacin, a fluoroquinolone antibiotic, carries a range of potentially serious risks despite its effectiveness in treating infections. It can cause severe allergic reactions, including life-threatening anaphylaxis, which requires immediate medical attention. Common side effects include nausea, diarrhea, headache, and photosensitivity. More serious adverse effects include tendinitis and tendon rupture, especially in people over 60 or those taking steroids, seizures, prolonged QT interval causing dangerous heart rhythm changes, and peripheral neuropathy. It can also cause liver toxicity, which may lead to jaundice or hepatic failure. Additionally, there is an increased risk of aortic aneurysm and dissection in certain patients. Due to these risks, it is important to follow medical advice closely, report any warning signs like severe diarrhea, rash, or muscle pain immediately, and avoid strenuous activity that may harm tendons. Levofloxacin should be used with caution, especially in older adults, those with heart, liver, or tendon issues, and children. Its use must always be supervised by a healthcare provider to minimize dangers and manage side effects effectively.