The Brisbane River is generally about 15 meters (49.12 feet) deep at its deepest points. In some areas, it was once as shallow as 1.5 meters but has sections currently reaching depths of around 15 meters.

The river is wide and deep especially as it approaches Moreton Bay, with widths varying from 100 meters to over 0.5 kilometers near the river mouth, allowing large ships to navigate through.

Overall, the maximum depth is approximately 15 meters, but depth varies along the length of the river depending on location and tidal influences.