The most common way to say "tired" in Spanish is [cansado](javascript:void(0)) (for a man) or [cansada](javascript:void(0)) (for a woman).

Other ways to express "tired" in Spanish:

• [Estoy cansado/a](javascript:void(0)) — I am tired (general, physical tiredness)
• [Estoy agotado/a](javascript:void(0)) — I am exhausted (very tired)
• [Estoy rendido/a](javascript:void(0)) — I am spent/exhausted
• [Estoy exhausto/a](javascript:void(0)) — I am exhausted
• [Estoy soñoliento/a](javascript:void(0)) or [somnoliento/a](javascript:void(0)) — I am sleepy/drowsy
• [Estoy harto/a](javascript:void(0)) — I am fed up (tired of something)

For example, "I am tired" is [Estoy cansado](javascript:void(0)) (man) or [Estoy cansada](javascript:void(0)) (woman).