Ozempic helps with weight loss primarily by mimicking a natural gut hormone called GLP-1 (glucagon-like peptide-1). This hormone affects several systems in the body to promote weight loss:

• Appetite suppression: Ozempic activates GLP-1 receptors in the brain, which signals fullness and reduces hunger, helping you eat less

• Slowing gastric emptying: It delays the rate at which food leaves the stomach, prolonging the feeling of fullness after meals and reducing overall food intake

• Improving blood sugar control: By stimulating insulin secretion when blood sugar is high and lowering glucagon secretion, it stabilizes blood sugar levels, which can reduce food cravings and prevent large blood sugar spikes that might otherwise increase hunger

These combined effects lead to reduced calorie consumption and weight loss. Clinical studies have shown that people using Ozempic can lose on average about 10–15% of their body weight over several months when combined with lifestyle changes like diet and exercise

. Ozempic is approved for type 2 diabetes but is often prescribed off-label for weight loss. A related drug, Wegovy, contains a higher dose of the same active ingredient (semaglutide) and is FDA-approved specifically for weight management

. In summary, Ozempic helps you lose weight by making you feel full sooner and longer, slowing digestion, and improving blood sugar control, which together reduce appetite and food intake