The distance from Chicago, Illinois to the state of Indiana varies depending on the specific location in Indiana. The air travel distance from Indiana to Chicago is about 135 miles (217 kilometers). When considering the distance to Indianapolis, the capital of Indiana, the driving distance from Chicago is approximately 180 to 182.6 miles, which usually takes around 2.5 to 4 hours by car depending on traffic. The air distance from Chicago O'Hare International Airport to Indianapolis International Airport is about 177.4 miles (285.5 kilometers).