Uber operates 24 hours a day, 7 days a week, meaning it runs late and basically anytime you need a ride, including during the night. However, availability of drivers may vary depending on the location and time, with potentially fewer drivers late at night or in more remote areas. Surge pricing may also apply during peak demand times such as weekends or major events.

For example, in cities like Las Vegas, Uber is known for reliable round-the- clock service, especially useful for nightlife, early morning trips, or airport transfers. It's recommended to consider designated pickup points and possibly schedule rides in advance during busy times to avoid long wait times.

In summary, Uber runs very late and basically all day long, but actual driver availability fluctuates by place and time.