A 21-pound turkey should cook for approximately 4½ to 5 hours at 325°F if unstuffed, or 4¾ to 5¼ hours if stuffed.

Cooking Guidelines

The general rule is to roast your turkey at 325°F, which allows for even cooking and helps retain moisture. For a 21-pound bird, plan on about 13-15 minutes per pound for an unstuffed turkey. However, cooking times can vary based on your oven's accuracy, the bird's exact size, and whether it's stuffed.

Checking for Doneness

Always use a meat thermometer to ensure your turkey is properly cooked. Insert the thermometer into the thickest part of the thigh without touching bone—the turkey is done when it reaches an internal temperature of 165°F. Start checking the temperature around the 4-hour mark and continue checking every 15 minutes until it reaches the safe temperature.

Resting Time

After removing the turkey from the oven, let it rest for at least 15-30 minutes before carving. This resting period allows the juices to redistribute throughout the meat, ensuring a moist and flavorful turkey.