Adderall XR (extended-release) is designed to release the medication gradually and typically lasts between 8 to 12 hours after a single dose. It usually starts working within 1 to 2 hours and provides symptom relief throughout the day, making it convenient for once-daily morning dosing

. The exact duration can vary depending on individual factors such as metabolism, age, weight, dosage, overall health, and tolerance. For example, a 20mg dose of Adderall XR generally lasts about 8 to 12 hours, but this can differ from person to person

. In summary:

• Onset: 1 to 2 hours after taking the dose
• Duration: 8 to 12 hours of effect
• Typical dosing: once daily in the morning

This extended duration contrasts with immediate-release Adderall, which lasts about 4 to 6 hours and often requires multiple doses per day