Boric acid suppositories typically take about 4 to 12 hours to fully dissolve after insertion, though this can vary depending on individual body factors like vaginal moisture and pH. Relief from symptoms such as bacterial vaginosis or yeast infection usually begins within a few days, but a full course of treatment typically lasts 7 to 14 days for the best results. It is important to complete the entire treatment period to ensure the infection is fully cleared and to prevent recurrence.