Flonase (fluticasone propionate) may begin working within 2 to 4 hours after the first dose, but it typically takes a few days to 2 weeks of daily use to experience the full and consistent effects for allergy relief. Many people start to feel some relief after the first day, but full effectiveness usually occurs after 3 to 4 days of regular use. For best results, it is recommended to use Flonase once daily, especially starting treatment at least 2 weeks before allergy season if possible.

Key Points

• Initial relief: 2 to 4 hours after first dose
• Full effect: 3 days to 2 weeks of daily use
• Recommended usage: once daily for continuous relief
• Combining with faster-acting medications can provide quicker symptom relief while Flonase builds effectiveness

This time frame applies to allergy symptom relief such as sneezing, runny nose, and nasal congestion. For sinus infection symptoms, improvement may take longer, averaging around 6 days.