Nurtec (rimegepant) typically starts to work within about 30 minutes to 2 hours after taking a dose. Most people experience some relief from migraine symptoms, including headache pain, nausea, and sensitivity to light or sound, within this timeframe. It is generally advised to take Nurtec as soon as a migraine starts for the best results. The effects of Nurtec can last for up to 48 hours, and when used preventively, it may take several weeks to notice a reduction in the frequency of migraines. In summary:

• Relief usually begins within 30 minutes to 2 hours.
• Maximum concentration in the body is reached around 1.5 hours.
• Effects can last 24 to 48 hours.
• Preventive benefits may take several weeks to become noticeable.

This timing can vary slightly depending on the individual and the specific use (acute treatment vs. prevention).