Weight loss on Ozempic typically begins gradually and varies by individual. Many people may start to notice some appetite suppression and subtle weight changes within the first few weeks, but significant weight loss usually occurs after 8 to 12 weeks when higher doses are reached

. Clinical studies show that:

• Some patients experience weight loss as early as 2 to 3 weeks, but this is less common

• On average, patients lose about 2% of their body weight in the first month

• By 3 months (around 12 weeks), average weight loss is about 6% of body weight

• At 6 months, weight loss can reach around 11% of body weight, with some losing 12-13 pounds or more depending on starting weight

• Long-term use (around 68 weeks) can result in up to 15% to 20% body weight reduction when combined with lifestyle changes like diet and exercise

Weight loss speed and amount depend on factors such as dose escalation, individual response, diet, exercise, and starting weight. Ozempic is usually started at a low dose and gradually increased to minimize side effects, which can delay the onset of significant weight loss

. In summary, noticeable weight loss often begins after 1 to 2 months, with more substantial results typically seen after 3 to 6 months of treatment, especially when combined with lifestyle modifications