A 22 lb turkey should be cooked at 325°F (160-165°C) for about 4 to 4.5 hours if unstuffed, and about 4.5 to 5.5 hours if stuffed. The key is to ensure the internal temperature reaches 165°F (74°C) in the thickest part of the breast to be safe to eat.

Cooking Time Guidance

• For an unstuffed 22 lb turkey, roast for approximately 4 to 4.5 hours.
• For a stuffed turkey of the same weight, expect about 4.5 to 5.5 hours due to the insulation effect of stuffing.
• Cooking times are based on roasting at 325°F (160-165°C).

Temperature and Safety

• Use a meat thermometer to check the internal temperature. The safe minimum internal temperature is 165°F (74°C) for the breast and around 180°F (82°C) for the thigh.
• Basting every 30 minutes helps keep the turkey moist and promotes even browning.

Additional Tips

• Allow the turkey to rest for at least 30 minutes after roasting to let the juices redistribute, which helps with carving and makes the meat more tender.
• Remove the giblets and neck from the cavity before cooking, rinse the turkey inside and out, and pat dry before seasoning and roasting.