The baking time for chicken varies depending on the cut and size:

• For boneless, skinless chicken breasts:
  • Small (about 5 oz): 18-20 minutes at 425°F (220°C)
  • Medium (about 7-8 oz): 20-22 minutes at 425°F (220°C)
  • Large (about 9 oz or more): 22-25 minutes at 425°F (220°C)
• Another approach is baking at 400°F for about 21-26 minutes for medium-sized breasts (6 oz each)
• Whole chicken or bone-in pieces typically take much longer, around 1 hour and 15 minutes at 350°F to 400°F depending on size
• The most reliable way to ensure doneness is to use an instant-read thermometer, cooking until the internal temperature reaches 165°F (74°C)
• Let the chicken rest 5-10 minutes after baking before slicing to keep it juicy

For juicy chicken breasts, baking at a higher temperature (425-450°F) for a shorter time is preferred over low and slow baking, which can dry the meat out.