To bake tilapia fillets, the common recommended time is about 10 to 15 minutes at a temperature of 400 to 425 degrees Fahrenheit. The tilapia is done when the fillets are white, tender, and flaky with a fork, and the internal temperature reaches 145°F (63°C). Thicker or larger fillets might require the longer end of this time range, up to 15 minutes, while smaller or thinner fillets cook more quickly, around 10-12 minutes. Here are some summarized guidelines:

• Bake at 400°F (200°C) for 10-12 minutes for small fillets; larger fillets may take up to 15 minutes.
• Bake at 425°F for 10-12 minutes for a crispier texture, especially if breaded.
• Check for doneness by flaking the fish with a fork; it should flake easily.
• For whole tilapia, bake for about 10 minutes per inch of thickness.

Overall, baking tilapia is fast and easy, usually done in 10 to 15 minutes depending on thickness and oven temperature.