To cook salmon in the oven, the general guideline is:

• Bake at 375°F (190°C) for about 12 to 15 minutes for individual portions (around 6 ounces), or 15 to 20 minutes for a larger 2-pound side of salmon

• Cooking time depends on the thickness of the salmon; a good rule of thumb is about 5 minutes per ½ inch of thickness

• The salmon is done when it flakes easily with a fork, looks opaque but still moist and glossy inside, and reaches an internal temperature of about 125°F to 140°F depending on your preferred doneness (medium-rare to well done)

• To keep salmon moist, baking at a moderate temperature and avoiding overcooking is key. Covering with foil or baking in foil packets helps retain moisture

• For a crispy top, you can broil the salmon for 2-3 minutes after baking

In summary, bake salmon at 375°F for roughly 12-20 minutes depending on size and thickness, checking for doneness by flaking or internal temperature to avoid drying it out