The number of calories burned running a mile varies primarily based on your body weight but is generally estimated around 100 calories per mile for an average person. This estimate comes from multiple expert sources including Dr. Daniel V. Vigil from UCLA and others

. Key details:

• A common rule of thumb is about 100 calories burned per mile for someone of average weight.
• Heavier individuals burn more calories per mile because it takes more energy to move a larger body. For example, a 120-pound person burns roughly 114 calories running a 10-minute mile, while a 180-pound person burns about 170 calories for the same distance and pace

• The calorie burn per mile is fairly stable regardless of running speed. Running faster burns more calories per minute but because the mile is completed faster, the total calories burned per mile stay roughly the same

• A more precise formula from a landmark study estimates calories burned as about 0.71 calories per pound of body weight per mile. So a 200-pound person would burn about 142 calories running one mile

• Running burns more calories than walking the same distance due to the vertical motion (bounce) involved in running, which requires more energy

In summary, you burn roughly 100 calories per mile on average, with the actual number depending mostly on your weight and less so on your running speed. For a personalized estimate, multiply your body weight in pounds by about 0.7 to get calories burned per mile.