The general estimate for calories burned running a mile is about 100 calories for an average-weight person. However, this number varies mainly based on body weight and somewhat on running efficiency and intensity.

• A common rule of thumb is that you burn roughly 0.63 to 0.71 calories per pound of body weight per mile. For example, a 120-pound person burns about 114 calories running a 10-minute mile, while a 180-pound person burns about 170 calories for the same distance and pace

• Running speed does not significantly affect calories burned per mile. Whether you run a slow or fast mile, the calories burned per mile remain fairly constant because running efficiency improves with speed

• Other factors that influence calorie burn include running mechanics, intensity (which affects post-exercise calorie burn), and sex, with heavier runners burning more calories due to the greater energy required to move a larger body

In summary, you can estimate calories burned running a mile by multiplying your weight in pounds by about 0.7. So, a 150-pound runner would burn approximately 105 calories per mile, while a 200-pound runner would burn around 140 calories

. This makes running an effective exercise for calorie burning, regardless of pace, with total calories burned scaling mostly with body weight.