The maximum amount of Tylenol (acetaminophen) you can take at once depends on the strength of the tablets and your overall daily limit. Generally:

• For adults, the typical single dose is 325 mg to 1000 mg every 4 to 6 hours. The maximum single dose should not exceed 1000 mg at one time

• Tylenol tablets commonly come in 325 mg (regular strength), 500 mg (extra strength), and 650 mg (extended-release) forms. The usual dose is 2 tablets every 4 to 8 hours depending on the product

• The maximum total daily dose for a healthy adult is generally 4000 mg (4 grams) per day. However, some manufacturers and experts recommend a lower maximum of 3000 to 3250 mg per day to reduce the risk of liver damage

• For example, with 500 mg extra strength tablets, you should take no more than 6 tablets (3000 mg) per day, and only 1-2 tablets (500-1000 mg) at a time

• It is important not to exceed the maximum daily dose and to avoid taking multiple products containing acetaminophen simultaneously

• People with liver problems or who consume alcohol regularly should consult a healthcare provider, as their safe maximum dose may be lower (e.g., 2000 mg per day or less)

Summary:

Tablet Strength| Typical Single Dose| Max Daily Dose (Healthy Adults)| Max Tablets per Day (Approx.)
---|---|---|---
325 mg| 1-2 tablets| 3250-4000 mg| 10-12
500 mg| 1-2 tablets| 3000-4000 mg| 6-8
650 mg (ER)| 1 tablet| ~3900 mg| 6

Always follow the dosing instructions on your product label and consult your healthcare provider if unsure. Do not exceed 1000 mg at once and do not take more than 3000-4000 mg in 24 hours to avoid risk of severe liver damage