A standard bottle of wine contains 750 milliliters , which is equivalent to approximately 25.4 fluid ounces. This is the most common size for wine bottles worldwide

. Here is a quick summary of common wine bottle sizes and their ounce equivalents:

Bottle Size| Volume (ml)| Volume (oz)
---|---|---
Piccolo (Split)| 187.5| ~6.3
Half Bottle (Demi)| 375| ~12.7
Standard Bottle| 750| ~25.4
Magnum| 1500| ~50.7
Jeroboam| 3000| ~101.4
Rehoboam| 4500| ~152.1

A standard 750 ml bottle typically yields about five 5-ounce glasses of wine

. Thus, if you are asking "how many ounces in a bottle of wine," the answer is about 25.4 ounces for the standard bottle size. Other bottle sizes vary proportionally from there.