For adults, the typical recommended oral dose of Benadryl (diphenhydramine) is 25 to 50 mg every 4 to 6 hours as needed, with a maximum of 6 doses (up to 300 mg) in 24 hours

. Specifically:

• You can take 1 to 2 tablets or capsules (usually 25 mg each) every 4 to 6 hours.
• Do not exceed 6 doses in a 24-hour period.
• For insomnia, a single 50 mg dose at bedtime is typical, with a maximum of 50 mg for that use

For children, dosing depends on age and weight:

• Children 12 years and older can take 25 to 50 mg every 4 to 6 hours, up to 6 doses per day (max 300 mg/day).
• Children 6 to 11 years old typically take 12.5 to 25 mg every 4 to 6 hours, max 150 mg/day.
• Children under 6 years old should only use Benadryl under a doctor's direction, and oral use is generally not recommended for those under 2 years

Topical Benadryl products (creams, gels, sprays) should be applied to the affected skin area up to 3 to 4 times daily, but not more than 4 times per day

. If you have any health conditions (like liver or kidney disease, asthma, heart disease), are pregnant, breastfeeding, or elderly, consult your doctor before use

. Always follow the dosing instructions on the product label or your doctor’s advice. In summary:

• Adults: 25-50 mg every 4-6 hours, max 300 mg/day, max 6 doses
• Children 6-11: 12.5-25 mg every 4-6 hours, max 150 mg/day
• Children under 6: only under doctor supervision
• Topical: apply up to 3-4 times daily, max 4 times

Avoid exceeding these limits to prevent overdose or side effects