C-reactive protein (CRP) levels indicate inflammation in the body, and their interpretation depends on the numeric value and clinical context:
- Normal CRP levels: Less than 1 mg/L is low risk; generally, below 3 mg/L is considered normal or low risk for cardiovascular disease
- Mild to moderate elevation: Levels between 1 and 10 mg/L may indicate mild inflammation or conditions such as autoimmune diseases, minor infections, or chronic conditions
- Elevated CRP levels above 10 mg/L: Considered abnormal and suggest significant inflammation or infection. Levels from 10 to 40 mg/L may correspond to mild infections; 40 to 100 mg/L to moderate infections; and above 100 mg/L to severe infections or conditions like sepsis
- Severe elevation: CRP levels above 50 mg/L (or mg/dL, depending on units) are usually associated with severe acute bacterial infections and may require urgent medical attention
- Life-threatening levels: CRP over 200 mg/L often signals serious infections such as sepsis, which is life-threatening and demands immediate treatment
In summary, CRP levels above 10 mg/L are generally considered dangerous as they indicate significant inflammation or infection, with levels above 50 mg/L pointing to severe infection and above 200 mg/L indicating critical conditions like sepsis. Interpretation must consider the individual's overall health and symptoms, and elevated CRP warrants prompt medical evaluation