You can donate plasma as often as twice a week, with at least one day between donations, according to FDA regulations in the U.S. This means you can donate plasma up to two times within a seven-day period, but not on consecutive days without a gap

. Other countries and organizations have slightly different guidelines:

• In Canada, you can donate plasma as often as once a week, depending on the donor program, with a minimum interval of 6 to 56 days between donations

• In Australia and New Zealand, plasma donation is allowed every two weeks

• In the UK, plasma donation can be done as often as every two weeks as well

Because plasma is mostly water and replenishes quickly (within 24-48 hours), donation frequency is higher than whole blood donation, which requires longer intervals (e.g., 56 days in Canada for males)

. However, factors such as recent surgery, tattoos, pregnancy, illness, and overall health can affect your eligibility and how often you can donate

. In summary:

• FDA (U.S.): Up to 2 times per week, with at least one day in between donations.
• Canada: About once a week or longer depending on the program.
• Australia/New Zealand/UK: Every two weeks.

Always ensure you are in good health, hydrated, and have eaten before donating plasma