To make a Potion of Weakness in Minecraft, follow these steps:

1. Gather Ingredients and Equipment:
   • Water bottles (fill glass bottles with water)
   • Fermented spider eye (crafted from sugar + brown mushroom + spider eye)
   • Brewing stand
   • Blaze powder (to fuel the brewing stand)
2. Crafting the Potion of Weakness:
   • Place blaze powder in the brewing stand’s fuel slot.
   • Put water bottles in the bottom slots of the brewing stand.
   • Add a fermented spider eye to the top slot.
   • Wait for the brewing process to complete, which will yield Potions of Weakness.
3. Optional Enhancements:
   • To extend the duration of the potion to 4 minutes, brew the Potion of Weakness with Redstone dust.
   • To make it throwable (Splash Potion of Weakness), add gunpowder to the Potion of Weakness in the brewing stand.

This potion decreases melee damage dealt by the affected entity and is especially useful for curing zombie villagers or weakening enemies

. Summary in brief:

• Fermented spider eye + water bottle + brewing stand + blaze powder → Potion of Weakness
• Add redstone dust to extend duration
• Add gunpowder to make splash potion

This is the simplest potion to brew as it does not require an awkward potion base