Pyrex is generally oven-safe, but with important precautions to prevent damage or injury. Key points:

• Temperature limit: Most Pyrex glassware is safe in a preheated oven up to 425°F (220°C). Exceeding this can increase risk of thermal shock and breakage.

• Handle with care: Do not use Pyrex that is cracked, chipped, or scratched. Damage can compromise integrity and lead to shattering in the oven or when handling.

• Avoid thermal shock: Do not transfer from freezer or fridge directly into a hot oven; allow gradual temperature changes and preheat the dish or bring it to room temperature first when possible.

• Lids and plastic parts: Plastic lids or any plastic components are not oven-safe and should be removed before baking. Only the glass/ceramic portion should go in the oven.

• Vintage considerations: Older Pyrex may have different durability; many vintage pieces are rated similarly for oven use but still subject to the same thermal-shock rules. Inspect for wear before use.

Practical tips for safe use:

• Preheat the oven and place the Pyrex dish in when the oven is at temperature to reduce uneven heating.

• Do not place a hot dish on a cold countertop or on a cold surface without a heat diffuser or trivet, which can cause thermal shock to the surface.

• Use oven mitts when handling hot Pyrex and avoid sudden temperature changes (e.g., don’t add boiling liquid to a cold dish or move a hot dish onto a cold plate).

If you have a specific Pyrex piece (model or age) and a recipe or temperature in mind, I can tailor the guidance to that piece and situation.