Micardis Plus is a medication used to treat hypertension, which is high blood pressure. It is a combination of two active ingredients: telmisartan and hydrochlorothiazide. Telmisartan belongs to a group of medicines called angiotensin II receptor blockers, which work by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow and increases blood pressure. Hydrochlorothiazide is a thiazide diuretic, which works by increasing the amount of urine produced by the kidneys, thereby reducing the amount of fluid in the blood vessels and lowering blood pressure.

Here are some additional details about Micardis Plus:

Positive effects:

• Micardis Plus has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone.
• Micardis Plus once daily produces effective and smooth reductions in blood pressure across the therapeutic dose range.

Negative effects:

• Adverse reactions previously reported with one of the individual components may be potential adverse reactions with Micardis Plus, even if not observed in clinical trials with this product.
• Drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus.

Ingredients:

• Each Micardis Plus 40 mg/12.5 mg tablet contains 40 mg telmisartan and 12.5 mg hydrochlorothiazide.
• Each Micardis Plus 80 mg/12.5 mg tablet contains 80 mg telmisartan and 12.5 mg hydrochlorothiazide.
• The tablets contain the following inactive ingredients: sodium hydroxide, meglumine, povidone, sorbitol, and magnesium stearate.