Mupirocin ointment is a topical antibiotic drug used to treat certain bacterial skin infections, such as impetigo, caused by Staphylococcus aureus (staph) or Streptococcus pyogenes (strep) bacteria. It comes in a strength of 2% or 20 mg/g of ointment. The active ingredient in mupirocin ointment is mupirocin, and each gram of the ointment contains 20 mg of mupirocin in a bland water miscible ointment base (polyethylene glycol ointment).

Positive aspects:

• Mupirocin ointment is effective in treating impetigo, with clinical efficacy rates of 93%.
• It is associated with fewer adverse effects than systemic anti-infective therapy.

Negative aspects:

• Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi.
• Mupirocin ointment is contraindicated in individuals with a history of sensitivity reactions to any of its components.
• If a reaction suggesting sensitivity or chemical irritation occurs with the use of mupirocin ointment 2%, treatment should be discontinued and appropriate alternative therapy for the infection instituted.

Ingredients or materials:

• Active ingredient: mupirocin
• Inactive ingredients: polyethylene glycol ointment, benzyl alcohol, cetomacrogol 1000, cetyl alcohol, mineral oil, phenoxyethanol, purified water, stearyl alcohol, and xanthan gum.