Scent by SIX is a fragrance brand that does not use ingredients of animal origin in their products. However, there is no information available on the specific ingredients or materials used in their fragrances.

Number Six Cologne by Caswell-Massey contains a variety of ingredients, including alcohol denat, water, ethylhexyl methoxycinnamate, butyl methoxydibenzoylmethane, ethylhexyl salicylate, BHT, yellow #5, benzyl alcohol, benzyl, and other natural extracts. The product is free from parabens, sulfates, and phthalates, and is cruelty-free. The full-size bottle contains 3 oz (88 ml) of cologne, while the travel-size vial contains 0.25 oz (7.5ml).

Fragrances are substances that possess strong-smelling organic compounds that have characteristic, pleasant odors. They can be made from natural or synthetic ingredients, and are used in many products as a perfume. Synthetic fragrance ingredients can either be nature-identical or artificial. Natural-identical synthetic fragrances are made from synthetically derived ingredients to have the same chemical composition as a fragrance found in nature. Artificial fragrances are made from synthetic ingredients and have a scent and/or chemical composition not known to be found in nature. There are thousands of registered fragrance ingredients made from five classes of compounds: alcohols, aldehydes, ketones, esters, and lactones.

While fragrances are regulated, fragrance suppliers have long enjoyed federal trade secret protections that allow them to hide the ingredients that make up their fragrances. This means that many fragrances contain secret, unlabeled, and often toxic chemicals that can cause harm to human health. Some of the chemicals used in fragrances, such as phthalates, have been linked to health risks.