Several airlines fly into Key West International Airport, including:
- American Airlines: non-stop service to Miami (MIA), Philadelphia (PHL), Charlotte (CLT), Dallas (DFW), Chicago (ORD), New York (LGA), and Washington D.C. (DCA) .
- Delta Airlines: non-stop service to Atlanta (ATL) and New York (LGA) .
- Silver Airways: non-stop service to Ft. Lauderdale (FLL), Orlando (MCO), and Tampa (TPA) .
- United Airlines: non-stop service to Houston (IAH), Newark (EWR), Washington-Dulles (IAD), and Chicago (ORD) .
- JetBlue Airways: non-stop service to Boston (BOS) and New York (JFK) .
- Allegiant Air: non-stop service to Tampa (TPA), Asheville (AVL), Indianapolis (IND), Sanford (SFB), Cincinnati (CVG), and Pittsburgh (PIT) .
Its important to note that some flights may only operate seasonally or with limited service during certain times of the year.