DHT blockers are medications and supplements that block dihydrotestosterone (DHT), a male sex hormone that binds to receptors in the scalp and causes hair loss that leads to male pattern baldness in genetically-susceptible men. DHT blockers work by either cutting down the levels of DHT in the body or inhibiting the effects of DHT at the scalp level. There are different types of DHT blockers, including natural or herbal DHT blockers and medical DHT blockers. Natural DHT blockers include saw palmetto, biotin, and nettle, while medical DHT blockers include finasteride and minoxidil. Finasteride is the only DHT blocker that has been clinically proven and approved to block the effects of DHT. DHT blockers are effective medications that treat androgenic alopecia or male pattern hair loss. However, before taking DHT blockers orally or applying them to the skin, it is important to consult with a doctor first.