Strychnine is a toxic alkaloid that can be fatal if ingested, inhaled, or administered intravenously. The extent of poisoning caused by strychnine depends on the amount and route of exposure, as well as the persons health condition at the time of exposure. The immediate signs and symptoms of strychnine poisoning usually appear within 15 to 60 minutes of ingestion. People exposed to low or moderate doses of strychnine may experience the following signs or symptoms:

• Agitation
• Apprehension or fear
• Ability to be easily startled
• Restlessness
• Painful muscle spasms possibly leading to fever and to kidney and liver injury
• Uncontrollable arching of the neck and back
• Rigid arms and legs
• Jaw tightness
• Muscle pain and soreness
• Difficulty breathing
• Dark urine
• Initial consciousness and awareness of symptoms

People exposed to high doses of strychnine may experience respiratory failure, brain death, and seizures within the first 15 to 30 minutes of exposure. Generalized muscle spasms may occur within 5 minutes of inhalation or intravenous administration, and within 15 minutes of ingestion but may take as long as 60 minutes to appear. Death is due to spasm of the respiratory muscles.

It is important to note that showing these signs and symptoms does not necessarily mean that a person has been exposed to strychnine, and other conditions may cause similar symptoms. If you suspect strychnine poisoning, contact Poison Control right away for help.