The May Blues is a term that refers to a sort of malaise that comes over Japanese people during May who have started a new life at the beginning of the year. However, in the context of the Persona 5 Royal crossword puzzle, the answer to the question "What are the May Blues?" is "Malaise". The crossword puzzle mini-game in Persona 5 Royal appears on the table in LeBlanc on certain days only, and offers the chance for players to gain a Knowledge point without passing time. To win the Crossword Puzzle, players simply need to solve the highlighted section using the hint and the letters on the right.