Gout is a type of inflammatory arthritis that causes pain and swelling in the joints, usually as flares that last for a week or two, and then subside. Gout is caused by a buildup of excess uric acid in the body, which can form sharp crystals in the joints. Uric acid is produced when the body breaks down purines, which are found naturally in the body and in certain foods, such as red meat and organ meats. When there is too much uric acid in the body, uric acid crystals can build up and settle into the joints, causing pain and inflammation.

Risk factors for developing gout include:

• Being male: Men are three times more likely than women to develop gout.
• Having high levels of uric acid in the body.
• Eating a diet rich in red meat, shellfish, and fructose.
• Drinking alcohol, especially beer.
• Being overweight or obese.
• Having certain health conditions, such as high blood pressure, diabetes, kidney disease, and heart disease.
• Taking certain medications, such as diuretics and immunosuppressants.

In summary, gout in males is caused by a buildup of excess uric acid in the body, which can form sharp crystals in the joints. Risk factors for developing gout include being male, having high levels of uric acid in the body, and eating a diet rich in red meat, shellfish, and fructose.