Upper and middle back pain in females can be caused by a variety of factors, including poor posture, overuse or injury of the muscles, ligaments, or discs that support the spine, a vertebra fracture, pressure on the spinal nerves from problems such as a herniated disc, and osteoarthritis. Other possible causes include spinal infections, lung cancer, and bladder or kidney infections. Upper back pain may also be due to muscle overuse or strain, usually due to repetitive motions or lifting items or children incorrectly. Hormone fluctuations can also cause back pain in females. Symptoms of upper and middle back pain include muscle tightness or stiffness, a dull, burning, or sharp pain, and weakness in the arms or legs, loss of bowel or bladder control, and numbness or tingling in the arms, legs, chest, or belly. If the pain gets worse and limits daily activities, it is recommended to talk to a doctor.