Gucci Mane's comments about Nicki Minaj have evolved over time. In a past controversy, his former manager claimed that Gucci Mane disliked Nicki Minaj because she refused to sleep with him, a claim that sparked controversy and was laughed off by Nicki Minaj. Despite earlier tensions, Gucci Mane and Nicki Minaj ended their feud and reunited musically in 2017, showing respect publicly. However, recently, Nicki Minaj launched a fierce social media tirade against Gucci Mane and his wife, Keyshia Ka'oir, accusing Keyshia of trying to imitate her and of keeping Gucci "sedated" in relation to his mental health struggles. Gucci and Keyshia have not directly responded to Nicki's latest accusations, but Keyshia seemingly reacted indirectly by calling the situation "embarrassing." This ongoing drama highlights a complex and sometimes strained relationship between Gucci Mane and Nicki Minaj, marked by past conflicts, reconciliations, and renewed tensions in 2025. Overall, Gucci Mane has shown both dislike and respect for Nicki at different times, with recent interactions mostly fueled by Nicki Minaj's critiques aimed at Gucci and his wife regarding his mental health management and their personal dynamics.