Alex Karev is a character from the TV show Greys Anatomy. Justin Chambers, the actor who played Alex Karev, left the show in the middle of season 16 to pursue other acting roles and career choices. The show decided not to kill off Alex Karev, but instead, he was written off in a way that surprised many fans. In the show, Alex Karev sent four handwritten letters to Jo, Meredith, Bailey, and Webber, explaining that he left Jo for his ex-wife Izzie Stevens. In the final episode that aired in November 2019, Alex was shown to be in Iowa to help his mom, but it was later revealed that he had gone to Kansas to be with Izzie. In the episode, Alex revealed in a letter to Meredith that Izzie called him five years ago to use embryos they froze years ago when they were married and she was undergoing chemo as part of her cancer treatment. The newly rekindled couple is now living on a farm in Kansas with their twin kids.