Mike Tirico had to abruptly exit NBC's coverage of the 2025 Kentucky Derby due to a severe allergic reaction to nuts. During the broadcast on May 3, 2025, Tirico began feeling unwell and was replaced mid-coverage by Ahmed Fareed. It was later clarified that Tirico's symptoms were caused by his nut allergy being triggered, which required him to use his EPIPen and receive treatment from EMTs. Although he recovered later that evening and confirmed he was feeling fine, he did not return to the broadcast that day

. Tirico, who has been a lead broadcaster for NBC Sports' Triple Crown coverage since 2017, explained that he had accidentally left his EPIPen behind during a recent appearance but is usually very careful due to his lifelong nut allergy. Social media viewers noted that his voice sounded congested and weak during the early coverage, consistent with an allergic reaction rather than a general illness

. In summary, Mike Tirico's departure from the 2025 Kentucky Derby broadcast was due to a significant nut allergy reaction, not a general illness, and he was treated promptly and is now recovering well