It is generally not recommended to drink alcohol while taking metronidazole. The combination of metronidazole and alcohol can cause a reaction, often referred to as a disulfiram-like reaction, in some people. Symptoms may include flushing, headaches, nausea, vomiting, and stomach cramps. There has been one reported death associated with this reaction. While several studies have investigated the reaction of metronidazole with alcohol and found evidence of the existence of this interaction to be absent or weak, it is best to err on the side of caution and avoid alcohol while taking metronidazole until more is known.

If you choose to drink while on the medication, it is important to be aware and monitor your body’s reaction. It is also recommended that patients speak with a healthcare provider about taking it with alcohol before beginning treatment with metronidazole and discuss any alcohol consumption plans. To ensure that the entire course of treatment is successful, it’s best to abstain from drinking alcohol for at least 72 hours after completing a round of Metronidazole.

Drinking alcohol within three days of taking metronidazole can cause additional unwanted effects, such as face flushing (warmth and redness), rapid heart rate, and liver damage. It is best to avoid alcohol while taking metronidazole, as alcohol can cause reactions in addition to the regular side effects of this drug.