what is a genetic disorder

what is a genetic disorder

1 year ago 33
Nature

A genetic disorder is a disease caused by changes or mutations in an individuals DNA sequence. These mutations can be due to an error in DNA replication or due to environmental factors, such as exposure to radiation or chemicals. Genetic disorders can be grouped into three main categories:

  • Single gene disorders: These are disorders caused by defects in one particular gene, often with simple and predictable inheritance patterns. There are three types of single gene disorders: dominant, recessive, and X-linked. Examples of single gene disorders include cystic fibrosis, sickle cell anemia, and Huntingtons disease.

  • Chromosome disorders: These are disorders resulting from changes in the number or structure of the chromosomes. Examples of chromosome disorders include Down syndrome and Turner syndrome.

  • Complex disorders: These are disorders that are caused by the simultaneous effect of many different genes, often in a complex interaction with environmental and lifestyle factors such as diet. Examples of complex disorders include diabetes mellitus, hypertension, and schizophrenia.

Genetic disorders can be inherited from one or both parents, or they can occur spontaneously due to a mutation that happens during a persons lifetime. Genetic testing can help identify genetic disorders, and treatment options vary depending on the specific disorder and its severity. It is important to seek care from an experienced specialist if you or a loved one has a genetic disorder, and support groups can also provide additional information and help.

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