According to multiple sources, including the Mayo Clinic, the CDC, and the National Heart, Lung, and Blood Institute, a healthy amount of weight to lose per week is generally 1 to 2 pounds. Losing weight at this rate is considered gradual and steady, and it is more likely to result in long-term weight loss success. Losing more than 2 pounds per week is generally considered too fast and may put you at risk of health problems such as muscle loss, gallstones, nutritional deficiencies, and a drop in metabolism. However, it is important to note that the amount of weight you can lose in a week may vary depending on factors such as your starting weight, age, sex, and activity level. It is also important to lose weight in a healthy way, through a combination of a reduced-calorie diet and increased physical activity, rather than through crash diets or very low-calorie diets.